Production method and application of oleoyl chloride


Release Date:

2024-06-11

Production method
By the reaction of oleic acid and phosphorus trichloride. Put oleic acid into the reaction pot, slowly add phosphorus trichloride under stirring, and the feeding temperature is controlled at 25-33 ℃. After the addition is completed, the temperature is raised to 55 ℃, and the lower phosphorous acid is separated after holding for 4h to obtain oleoyl chloride.
Use

Used as an intermediate in organic synthesis. The detoxification can be obtained by acylation of 2-sulfo-4-aminoanisole with oleoyl chloride.